Four patients with serious illnesses arrive at NIH's Building 10 to enter potentially groundbreaking clinical trials. The patients resting their hopes for a cure at this brilliant facility include a firefighter battling leukemia, a mother with metastatic melanoma overtaking her body, a woman fighting sickle cell disease and a little girl with Job's syndrome.
While a leukemia patient recovers from a near-death experience, a woman battling metastatic melanoma weighs her treatment options. Meanwhile, a woman fighting sickle-cell disease and a little girl with Job's syndrome receive highly experimental bone marrow transplants.
Patients with leukemia, metastatic melanoma, sickle-cell disease and Job's syndrome meet with their doctors one last time. After receiving a variety of treatments, it's time to learn whether or not the experimental procedures were successful and what the future holds for them.